NUCLEOTIDE COMPOSITION OF PENTOSE NUCLEIC ACIDS FROM YEAST AND MAMMALIAN TISSUES
نویسندگان
چکیده
منابع مشابه
The composition of the pentose nucleic acids of yeast and pancreas.
The historically understandable attempts to simplify the problem of nucleic acid structure by the formulation of the tetranucleotide hypot.hesis have found their classical exposition in Levene’s monograph of 1931 (1). The same tendencies are expressed, less precisely, in statements found in many text-books according to which the nucleic acid unit, having a molecular weight of about 1200, contai...
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The nucleic acids fall into two broad categories. The desoxypentose nucleic acids (DNA), in mammalian tissues, are found only in cell nuclei associated with the chromosomes (1,2). The pentose nucleic acids (PNA) are chiefly cytoplasmic (3), but are also found in smaller amounts in the nucleolus (4) and in the residual chromosomes (5, 1). Various studies have shown that the phosphorus of the des...
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Previous publications from this laboratory (l-3) have described the composition and some chemical properties of certain specimens of ribonucleic acids and of fractions derived from them. Because of the vagueness presently inherent in the term “nucleic acid,” it is believed that any specimen which is studied for any purpose should be characterized by many properties in order to facilitate compar...
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Formalin-fixed paraffin-embedded (FFPE) tissues are an important sample source for ret‐ rospective studies. Despite its ability to preserve proteins and cell morphology, formalin hinders molecular biology tests since it fragments and chemically modifies nucleic acids, especially RNA. Although several studies describe techniques that allow extracting nu‐ cleic acids from FFPE tissues, so far the...
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RNA.DNA hybridization experiments suggest differences between the DNA from the liver and spleen of the same animal (rabbit) and between the RNAs from lymph nodes stimulated by different antigens. A larger proportion of spleen DNA than of liver DNA was complementary to the RNA isolated from antigen-stimulated lymph nodes. No difference between liver and spleen DNA was observed in hybrids formed ...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1950
ISSN: 0021-9258
DOI: 10.1016/s0021-9258(18)56285-2